Liverpool have been drawn to face Sparta Prague in the next stage of the Europa League with three other British clubs in the round of 16.
West Ham and Brighton will go up against West Ham and Roma respectively while Rangers have been drawn to face Benfica.
All four British teams avoided having to play in the tricky play-off round, advancing straight to the round of 16 after topping their respective groups.
Teams that finished third in the Champions League groups dropped down into the Europa League in the previous round.
The Europa League round-of-16 draw has been made
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But Benfica and AC Milan were the only two teams that competed in the Champions League that progressed to the round of 16.
They were both included as one of the unseeded teams in the draw, along with Roma, Marseille, Sparta Prague, Sporting Lisbon, Qarabag and Freiburg.
Liverpool, West Ham, Brighton and Rangers were all in the seeded pot, meaning they weren't able to draw one another.
Atalanta, Bayer Leverkusen, Villarreal and Slavia Prague were the other four seeded teams.
Jurgen Klopp will be hoping his side can go all the way to Dublin for one final European adventure before his departure at the end of the season.
The last time Liverpool competed in the Europa League they finished as runner-up back in 2016 during Klopp's first season in charge of the club.
West Ham will be aiming to pick off where they left off in Europe having only dropped three points in their group.
Brighton also impressed having topped a group that included European giants Marseille and Ajax.
West Ham dropped just three points in their group
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Rangers boss Philippe Clement has helped carry the side back to the top of the Scottish Premiership since the Europa League group stage.
And he'll be hoping they can carry their league form into the knockout phase of the Europa League.
The first legs are scheduled for March 7 with the second legs taking place a week later on March 14.
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Qarabag are the first team from Azerbaijan to make it to the round-of-16
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Full Europa League round-of-16 draw
Sparta Prague vs Liverpool
Marseille vs Villarreal
Roma vs Brighton
Benfica vs Rangers
Freiburg vs West Ham
Sporting vs Atalanta
AC Milan vs Slavia Prague
Qarabag vs Bayer Leverkusen
