Emergency services have since blocked off the entrance to the building in Brisbane
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An "unknown substance" has been found in a building in Brisbane, Australia, prompting an emergency evacuation with 25 people left needing medical treatment.
They were reportedly exposed to the substance at 2.45pm, Queensland Ambulance Service (QAS) said.
Three floors of the building on the corner of George St and Margaret St have been evacuated, with emergency services blocking off the entrance to the building.
The service said the patients’ symptoms were minor.
Staff were reported as feeling unwell and complained of a strange smell coming from inside the building.
The 20th, 21st and 22nd floors were quickly evacuated, with the rest of the building soon following suit, according to 9 News.
Around 250 people in total were evacuated from the premises.
A scientific team was sent up the floors to try and determine the cause of the "unknown substance".
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They are understood to be carrying out air testing to establish what prompted the incident.
QAS posted on social media: "Paramedics are assessing 11 patients for very minor symptoms after they were reportedly exposed to an unknown substance in a building on George St around 2.45pm."
The service later gave an update on the ongoing situation.
"Paramedics assessed 25 people after they were reportedly exposed to an unknown substance and several floors were evacuated at a building on George Street in Brisbane City," they posted.
Emergency services were called to 41 George Street and the road remains closed
PA"Some patients reported very minor symptoms, however no one required transport to the hospital."
Roma Street Area Commander Steven Marmotta told 7NEWS that road closures on George St and Margaret St were expected to be lifted on Thursday evening.“We are conscious of the traffic inconvenience—as soon as we determine that (the building) is clear, we’ll move and open up (the roads),“ Marmotta said.