Four pedestrians were rushed to hospital after being struck by a car on Shaftesbury Avenue in London's West End during the early hours of Christmas Day.
One victim remains in life-threatening condition following the incident, which occurred at 00:45hrs when a vehicle was reported driving on the wrong side of the road.
The Metropolitan Police responded to the scene after receiving reports of a road traffic collision on the central London street.
A 31-year-old man has been arrested on suspicion of attempted murder in connection with the incident.
Police cordon on Shaftesbury Avenue
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Police cordon
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Deputy Assistant Commissioner Stuart Cundy said: "Officers responded quickly to this report, working closely with City of London Police to arrest a man within minutes."
Police have established multiple cordons at the scene, with several areas remaining closed for investigation throughout Christmas Day.
Detectives are rapidly progressing their investigation into the incident, which is believed to have stemmed from an altercation at a nightclub.
Police say the suspect became involved in the dispute at the venue before getting into his vehicle and mounting the pavement.
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Bloodied items on Shaftesbury Avenue
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Bloodied items on Shaftesbury Avenue
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The collision occurred in one of London's busiest entertainment districts, with Shaftesbury Avenue home to numerous nightclubs and late-night venues.
Police have confirmed this was an isolated incident and not terrorism-related.
The Metropolitan Police are urging any witnesses to come forward with information about the Christmas morning collision.
Members of the public can contact police on 101 or post information to @MetCC, quoting reference CAD 233 of 25 December.
Those wishing to remain anonymous can contact the independent charity Crimestoppers on 0800 555 111.
Police outside the cordon at Shaftesbury Avenue
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Police Cordon in Place by the Gielgud Theatre
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In an update just before midday, a police cordon could be seen in place on Shaftesbury Avenue in London’s West End.
Blood and items of clothing including a jacket, shoes and a hat are strewn across the pavement in front of a Caffe Concerto.
The cordon stretches between the Gielgud Theatre, where the musical Oliver is performed, and Sondheim Theatre, home to Les Miserables.
A further police cordon is in place on Archer Street and Great Windmill Street, covering the Windmill Soho nightclub and other venues in the city centre.
